Overview
Elashoff Consulting is a biostatistics consulting company specializing in genomics/genetics analysis and clinical trials.
Genomics
| Analysis We provide gene expression, genetics, and proteomics analysis services for academic investigators, institutes, and the biotech/pharma industry. Please see our analysis page for complete details on the methodologies we use, as well as specific case studies. Experience includes disease analysis, toxicogenomics, haplotype analysis, biomarker identification, pathway analysis, mass spec, 2D gels, and prediction of efficacy/safety responses. |
| Toxicogenomics Predictive toxicology based on genomics poses challenging statistical issues. We can help in your toxicogenomic efforts using our extensive experience in designing studies, identifying biomarkers, and developing predictive models. Our toxicogenomics page has more detials on our approach. |
| Cross Platform A specific area of expertise is in cross-platform / cross-laboratory normalization of microarray data. Benefits of these capabilities include: a) decreased variability, increased precision in array analyses, b) ability to leverage multiple studies for increased power, and c) ability to use reference databases in combination with your own studies. |
| Web Database We can also provide analysis results for your studies in a web-based analysis database. This database includes: significant gene lists, fold change/ p-value tables, QC and demographic analysis, plots (PCA, clustering, etc.), gene search page, pathway/gene ontology analyses hyperlinked to individual genes, and hyperlinks to public sources such as Pubmed. |
Clinical Trials
| Analysis We provide biostatistical analysis of phase 2/3/4 clinical trials. Therepuetic areas in which we have experience include asthma/allergy, antiviral, antibiotics, oncology, metabolic, arthritis/pain, and others. |
| Regulatory We also specialize in regulatory services for the biotech/pharma industry, focusing on advisory committee preparation and genomic data submissions. The regulatory page has a description of our extensive experience in regulatory issues. |
| Patient Profiles An emerging area in the clinical trial field is patient profiles, individualized displays of patient data for regulatory/safety reviews. Elashoff Consulting can generate patient profiles from your existing clinical databases, click here for more information. |
| Data Mangagment We can help you with clinical data management for small and large studies. Click here for more details. |
